Anti-Anemic Potential of a Herbal Recipe Against Phenylhydrazine-Induced Anemia in Rats

نویسندگان

چکیده

Anemia is characterized by an abnormal decrease in the level of hemoglobin or number red blood cells blood. It a public health problem that mainly affects pregnant women and young children. In present study, objective was to evaluated anti-anemic potential recipe composed three medicinal plants, Xylopia aethiopica (Dunal) A. Rich, Zanthoxylum leprieurii (GUILL) and Harungara madagascariensis (LAM), used treat sickle cell anemia rats. Aqueous hydroethanol extracts were first prepared quantitative phytochemical tests carried out. Then, activity assessed. The induced animals intraperitoneal injection phenylhydrazine at repeated dose 40 mg/kg bw for two days. Treatment out with aqueous plant doses 400 800 bw. obtained results indicated contains total phenols (43.31±0.92 mg GAE/g 33.82±0.6 GAE /g dry weight), flavonoids (17.07±0.89 QE 19.76±1.15 QE/g weight) tannin (8.65±0.01 26.5±0.95 Cat E/g decocted respectively. effectively corrected after 21 days oral administration significantly increased (P < 0.05), count 0.001), hematocrit 0.01) as early 7th treatment compared untreated controls. These show aethiopica, possess antianemic properties.

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ژورنال

عنوان ژورنال: Journal of Diseases and Medicinal Plants

سال: 2023

ISSN: ['2469-8202', '2469-8210']

DOI: https://doi.org/10.11648/j.jdmp.20230902.12